Pathways

Studies (2)

reviewpositivenicotinic-acidn/a

Emerging roles of GPR109A in regulation of neuroinflammation in neurological diseases and pain

Summary of GPR109A (niacin receptor) role in inflammation of the nervous system, especially the brain, and how activation of GPR109A plays a role in healing may conditions such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, and pathological pain.

animalpositivenicotinic-acidmouse

Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system

Niacin via its ability to enhance macrophage and microglia is great for repairing (myelin) sheaths that protect nerve fibers, which deteriorate in diseases like multiple sclerosis.